UserAssist

NTUSER.DAT\Software\Microsoft\Windows\CurrentVersion\Explorer\UserAssist\{GUID}\Count

UserAssist tracks programs launched through the Windows GUI — Start Menu, Desktop and Explorer. It records a run count and the last execution timestamp for each item, ROT-13 encoded to obscure paths from casual inspection. This is one of the few artifacts that directly attributles execution to a human clicking something, not a background service.

Key Name {ROT-13 encoded executable path} — REG_BINARY value containing run count and last execution timestamp (FILETIME)
Trace Type Execution
Hive NTUSER.DAT
Last Write Time The key's Last Write Time reflects the most recent GUI launch of any item in that GUID bucket — correlate with the per-value timestamp for precise last-run attribution.
User Specific Yes  Lives entirely inside NTUSER.DAT. Data is unique to each user profile and cannot be created by background or SYSTEM processes.

Forensic Value

For more Info check out these Articles: MuiCache, BAM, Prefetch